Prevention of Opioid Addiction
نویسندگان
چکیده
Opioid addiction is classified as a Substance Use Disorder (SUD), complex and chronic health condition with physical, social, psychological consequences. While there no cure for it, we present novel approach towards preventing hallmark feature of addiction-- the opiate withdrawal syndrome. Opioids exert numerous effects, acutely chronically, on nervous system physical dependence, tolerance, being most adverse features. The degree opioid dependence can be quantified by frequency and/or intensity behavioral expression seen after abrupt termination consumption or treatment an antagonist such naloxone. Although Central Nervous System (CNS) primary area impact, involvement immune in modifying CNS phenomena was suggested nearly two centuries ago proved several groups within last few decades. Through series studies immunomodulators alpha interferon, cyclosporine A, cortisol, preclinical experiments show that administration these agents prior to morphine exposure prevents addiction. This review provides updates current developments management epidemic overview preventative immunomodulation repetitive means addressing one underlying symptomatology driving epidemic.
منابع مشابه
Treatment of Opioid Addiction
The College in New Brunswick was reluctant to arbitrarily select one approach over the other, even granting the similarities. It was felt appropriate to allow physicians to adopt one of these established approaches to guide them. They could then modify their approach as they gain experience. That said, for the sake of some consistency, the College can point to the most recent guidelines from No...
متن کاملOpioid pharmacogenetics of alcohol addiction.
Alcohol addiction is one of the most common and devastating diseases in the world. Given the tremendous heterogeneity of alcohol-addicted individuals, it is unlikely that one medication will help nearly all patients. Thus, there is a clear need to develop predictors of response to existing medications. Naltrexone is a μ-opioid receptor antagonist, which has been approved in the United States fo...
متن کاملHepatitis in Opioid Addiction Treatment
Links: [1] https://www.buppractice.com/node/103 [2] http://dpt.samhsa.gov/pdf/HepC_draft_monograph_5-8-2006.pdf [3] https://www.buppractice.com/taxonomy/term/28 [4] https://www.buppractice.com/taxonomy/term/116 [5] https://www.buppractice.com/taxonomy/term/50 [6] https://www.buppractice.com/taxonomy/term/52 [7] https://www.buppractice.com/taxonomy/term/61 [8] https://www.buppractice.com/taxonom...
متن کاملManaging opioid addiction with buprenorphine.
Legislation has enabled physicians to treat opioid-dependent patients with an office-based maintenance program using buprenorphine, a partial mu-opioid receptor agonist. Clinical studies indicate buprenorphine effectively manages opioid addiction. Buprenorphine is more effective than placebo for managing opioid addiction but may not be superior to methadone if high doses are needed. It is compa...
متن کاملUse and misuse of opioid agonists in opioid addiction.
Although methadone (an opioid agonist) and buprenorphine (a partial opioid agonist) have evidence to support their use in treating opioid use disorder, they remain misunderstood and underutilized. In this article, we outline the risks and benefits of using these drugs as maintenance therapy in opioid-dependent patients.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of biomedical research & environmental sciences
سال: 2021
ISSN: ['2766-2276']
DOI: https://doi.org/10.37871/jbres1304